NCT00793715

Laparotomy Versus Percutaneous Puncture in Patients With Abdominal Compartment Syndrome During Acute Pancreatitis

Decompressive Laparotomy With Temporary Abdominal Closure Versus Percutaneous Puncture With Placement of Abdominal Catheter in Patients With Abdominal Compartment Syndrome During Acute Pancreatitis:Multicenter, Randomised, Controlled Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Belgrade · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Decompressive laparotomy with temporary abdominal closure, will decrease of overall mortality and major morbidity in patients with abdominal compartment syndrome during acute pancreatitis in comparison with percutaneous puncture with placement of abdominal catheter.

Detailed description

We anticipated that decompressive laparotomy with temporary abdominal closure, beside all potentially negative side effects that early open surgery carries in patients with acute pancreatitis, results in decrease of overall mortality and major morbidity. The DECOMPRESS study is designed to compare effects of decompressive laparotomy with temporary abdominal closure and percutaneous puncture with placement of abdominal catheter in patients with abdominal compartment syndrome during acute pancreatitis.

Conditions

• Mortality
• Acute Pancreatitis

Interventions

Type	Name	Description
PROCEDURE	Decompressive laparotomy with temporary abdominal closure	Surgical intervention including midline incision with temporary abdominal closure and several planed staged relaparotomies
PROCEDURE	Percutaneous puncture with placement of abdominal catheter	Installation of abdominal catheter percutaneously via abdominal centesis 2cm bellow the umbilicus

Timeline

• Start date: 2010-07-01
• Primary completion: 2012-06-01
• Completion: 2013-06-01
• First posted: 2008-11-19
• Last updated: 2010-07-26

Locations

5 sites across 1 country: Serbia