Clinical Trials Directory

Trials / Completed

CompletedNCT00787410

An Open-label, Phase II Trial of ZD1839 (IRESSA) in Patients With Malignant Mesothelioma

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
23 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is a multicentre, open label, non-comparative, two stage phase II trial to assess the activity of ZD1839 (IRESSA) in patients with malignant mesothelioma. Patients will receive trial treatment as first-line therapy, administered continuously once daily until the completion of six 4-week cycles of treatment, disease progression, unacceptable toxicity or withdrawal of consent. Patients continuing to show evidence of response, disease stabilization or clinical benefit from ZD1839 may continue to receive therapy beyond completion of the trail.

Conditions

Interventions

TypeNameDescription
DRUGZD1839250mg tablet, once daily, orally administered

Timeline

Start date
2003-09-01
Primary completion
2008-04-01
Completion
2008-04-01
First posted
2008-11-07
Last updated
2012-06-06

Source: ClinicalTrials.gov record NCT00787410. Inclusion in this directory is not an endorsement.