NCT00786721

Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort

Diffuse Optical Spectroscopy Measurement Technique is Helping Develop More Effective Diagnostic Tools and Therapeutic Regimes for Diabetes, Metabolic Syndrome and Other Mitochondrial Diseases Some Time in the Future

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 9 (actual)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

There has been increasing support for our hypothesis that mitochondrial dysfunction plays an important role in the etiology of Type 2 Diabetes Mellitus and the overlapping Metabolic Syndrome.

Detailed description

Once the mitochondrial defect(s) of these subjects has been defined, the data will be used to develop two non-invasive screening tools to detect mitochondrial defects in Diabetes Mellitus and Metabolic Syndrome patients. The device call Diffuse Optical Spectroscopy develope at Beckman Laser Instituteis is non-invasive measurement technique, to measure the properties of the muscle tisuue and vascular activity (calf, bicep, or the brain)to evaluate the patient's metabolic status and and to assess muscle mitochondrial OXPHOS function.

Conditions

• Metabolic Syndrome
• Type 2 Diabetes Mellitus

Interventions

Type	Name	Description
DEVICE	Diffuse Optical Spectroscopy	muscle properties scanning

Timeline

• Start date: 2006-11-01
• Primary completion: 2010-08-01
• Completion: 2010-08-01
• First posted: 2008-11-06
• Last updated: 2022-11-01

Locations

1 site across 1 country: United States