NCT00786539

Mitochondria Inborn Errors of Metabolism and ANT Defects in Mitochondria Diseases

Investigation of the Nature and Prevalence of Mitochondria Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 18 (actual)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: All
• Age: 1 Day
• Healthy volunteers: Not accepted

Summary

The objective of this research protocol is to continue investigation of the nature and prevalence of mitochondria disease and to aid patients and health care providers in the understanding of these complex disorders. This research study brings together many clinical sub-specialists to address the etiology of these disorders and to develop more effective approaches for their diagnoses and more reliable prognoses.

Detailed description

The non-invasive device named Diffuse Optical Spectroscopy developed at the Beckman Laser Institute is to be used to measure various physiological parameters. Since mitochondria produce most of the energy necessary for cellular function, their efficacy is most important for systems with a high energy demand like the brain, heart, skeletal muscle, kidney, liver, and endocrine tissues. As a result, mitochondria diseases usually manifest as complex, multi-organ disorders, requiring multispecialty investigations.

Conditions

• Mitochondrial Disease

Interventions

Type	Name	Description
DEVICE	Diffuse Optical Spectroscopy	mitochondria

Timeline

• Start date: 2006-10-01
• Primary completion: 2015-05-01
• Completion: 2015-05-01
• First posted: 2008-11-06
• Last updated: 2022-10-20

Locations

1 site across 1 country: United States