NCT00784797

Misopristol Versus Pitocin for Second Trimester Abortion

Comparison Between Misopristol and Pitocin After Mifepristone Preparation for Second Trimeter Abortion

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 145 (actual)
• Sponsor: Hadassah Medical Organization · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Second trimester abortion can be done surgically or medically. Medical abortion with mifepristone and misopristol is one of the common protocol, but misopristol have high rate side effect. The investigators recent study proved the efficacy of pitocin after mifepristone in second trimester abortion with minimal side effects. Working hypothesis and aims: To compare misopristol and pitocin after mifepristone preparation in second trimester in seccess rate, interval to abortion, side effects and patient satisfaction.

Conditions

• Abortion, Missed

Interventions

Type	Name	Description
DRUG	mifepristone and misopristol	200 mg mifepristone and after 48 hours vaginal misopristol 800 mgr followed by oral misopristol 400 mgr every 3 hours for maxamum 5 doses
DRUG	mifepristone and oxytocin	200 mg mifepristone followed 48 hours with high dose oxytocin drip (9 unit per hour)

Timeline

• Start date: 2009-01-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2008-11-04
• Last updated: 2013-11-21

Locations

1 site across 1 country: Israel