NCT00784472

Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL

Visceral Pain Originating From the Upper Urinary Tract - a Randomized Controlled Trial on the Effect of Morphine and Oxycodone in Patients Undergoing Percutaneous Nephrolithotomy (PCNL)

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 55 (actual)
• Sponsor: Katja venborg Pedersen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the effect of oxynorm versus morphine after operation for kidney stone (PCNL). In addition the relationship between pain symptoms and referred sensory and trophic changes will be examined in the patients before and after the operation.Finally a blood sample is analysed to investigate pharmaca-genetics.

Detailed description

Primary outcome: the amount of opioid (morphine or oxynorm) used the first 4 hours postoperatively. Secondary outcome: side effect to the opioids, pain score, pain threshold to electrical stimulation and pressure before and after operation, pharmacogenetics, size of referred pain area.

Conditions

• Kidney Stones

Interventions

Type	Name	Description
DRUG	oxycodone	intravenous according to patients weight, pn.
DRUG	morphine	intravenous administration according to patients weight, pn.

Timeline

• Start date: 2008-12-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2008-11-04
• Last updated: 2012-07-09

Locations

1 site across 1 country: Denmark