NCT00783952

Validation of Mixed Venous Blood Oxygen Saturation Obtained With a Novel Mathematical Equation

Validation of Mixed Venous Blood Oxygen Saturation Obtained With a Novel Mathematical Equation Using Arterial Oxygen Saturation and Various Local Tissue Oxygen Saturations.

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test a new way to measure the oxygen level in the mixed venous blood system (the system that carries blood collected from all over the body to the heart), which is a very important monitoring tool for the overall oxygen delivery to all our tissues. This new way measures the oxygen level in the mixed venous blood from outside the body, instead of measuring from the inside through a catheter (a thin, flexible plastic tube) that is placed by breaking the skin.

Detailed description

Study terminated because of inability to recruit subjects

Conditions

• Mixed Venous Oxygen Saturation
• Tissue Oxygenation

Interventions

Type	Name	Description
DEVICE	Cerebral/Somatic Tissue Oximeter device	Measurement of tissue oxygen saturation and simultaneous sampling for blood gas analysis. Four sensors of the 'Cerebral/Somatic Tissue Oximeter' device will be placed on subject's both sides of the forehead, palm and calf area. Simultaneously, blood samples will be drawn from the pulmonary artery catheter and arterial line for blood gas analyses. The values obtained from the device measurements will be used in a new equation to calculate the mixed venous oxygen saturation. The calculated value will be compared to the real value from the blood gas analysis for accuracy.
DEVICE	Pulmonary artery catheter	Blood will be drawn form the pulmonary artery catheter for measurement of mixed venous oxygen saturation.

Timeline

• Start date: 2008-11-01
• Primary completion: 2013-01-01
• Completion: 2013-01-01
• First posted: 2008-11-03
• Last updated: 2017-04-20
• Results posted: 2017-04-20

Locations

1 site across 1 country: United States