NCT00782938

The Role of Serum Anticholinergic Activity in ACVB Patients

Serum Anticholinergic Activity (SAA) and BIS-EEG as Potential Markers for Cognitive Ability and/or the Anticholinergic Medication in ACVB Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Heidelberg University · Academic / Other
• Sex: All
• Age: 55 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Drugs with anticholinergic potential increase the risk of postoperative transient and persistent cognitive dysfunction especially in cardiac patients. The investigators main goal is to identify preoperative risk factors and to monitor postoperative patients' state in relation to SAA activity and bilateral BIS-EEG changes.

Conditions

• Acetylcholine
• Cognition
• BIS-EEG

Timeline

• Start date: 2008-05-01
• Primary completion: 2009-12-01
• Completion: 2010-01-01
• First posted: 2008-10-31
• Last updated: 2010-01-14

Locations

1 site across 1 country: Germany