NCT00780572

Implementation of Real-time ADE Surveillance and Decision Support

Implementation of Real-Time ADE Surveillance and Decision Support

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 595 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if an electronic alerting technology improves time to intervention for possible ADEs, identify what factors affect adoption of ADE alerts, and whether there is a cost benefit associated with the alerting technology.

Detailed description

Inpatient adverse drug events (ADEs) continue to be a major source of morbidity and mortality despite advances in computerized drug safety measures. Reports on the ability of computerized ADE alerts to prevent and mitigate ADEs are lacking. The aims of this project are to 1) Assess organizational, social, and cognitive factors that affect adoption of real-time ADE alerting technology; 2) Analyze the effect of the ADE alerting technology on management and rate of ADEs; and 3) Estimate the cost-benefit of the ADE alerting technology. This study will use a patient randomized design of computerized real-time ADE alerts intended for primary and secondary prevention of ADEs. The ADE alerts promise to reduce mortality, morbidity, and costs due to ADEs. This study will quantify the effect of the alerts in the hands of first-year medical residents and pharmacists. The study will explore the associations of organizational and soci-cognitive barriers and facilitators with the adoption of the ADE alert technology. At the cognitive level, it will explore whether ADE Alerts change user bias in diagnosing ADEs or whether the alerts heighten sensitivity to drug problems.

Conditions

• Adverse Drug Events

Interventions

Type	Name	Description
BEHAVIORAL	ADE alert assistant	A note in CPRS alerting providers that patients are at risk for an adverse event based on prescription and lab value histories.

Timeline

• Start date: 2008-12-01
• Primary completion: 2010-09-01
• Completion: 2011-03-01
• First posted: 2008-10-27
• Last updated: 2015-12-21
• Results posted: 2015-11-18

Locations

1 site across 1 country: United States