NCT00776477

The Clopidogrel and Aspirin After Surgery for Coronary Artery Disease

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: China National Center for Cardiovascular Diseases · Other Government
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Clopidogrel is a antiplatelet agent and is effective at reducing intimal hyperplasia in animal models of thrombosis.Several large clinical trials have demonstrated that clopidogrel with aspirin can reduce ischemic events and mortality in patients with atherosclerotic disease,therefore the combination of two antiplatelets might be useful to prevent patients received coronary artery bypass graft surgery from Saphenous vein graft disease. the aim of this study is to estimate the safety and efficacy of clopidogrel and aspirin therapy versus aspirin alone in patients after CABG.

Conditions

• Atherosclerosis

Interventions

Type	Name	Description
DRUG	clopidogrel and aspirin	clopidogrel 75mg daily and aspirin 100mg daily
DRUG	aspirin	aspirin 100mg daily

Timeline

• Start date: 2007-12-01
• Primary completion: 2008-12-01
• First posted: 2008-10-21
• Last updated: 2008-10-21

Locations

1 site across 1 country: China