NCT00768690

A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of ABT-333

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: Abbott · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine multiple dose safety, tolerability and pharmacokinetics of ABT-333 under nonfasting conditions in healthy adult subjects, and to determine the effect of single dose administration of ketoconazole on steady state ABT-333 pharmacokinetics

Detailed description

Phase 1, Blinded, Randomized, Placebo-controlled Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-333

Conditions

• HCV Infection

Interventions

Type	Name	Description
DRUG	ABT-333	Capsule, or powder drug substance from the capsule powder mixed in an alternate vehicle. For additional information refer to arm description.
DRUG	ketoconazole	Tablet, see arms for intervention description
DRUG	placebo	Capsule or powder drug substance from the capsule powder mixed in an alternative vehicle. For additional information refer to arm description.

Timeline

• Start date: 2008-10-01
• Primary completion: 2009-02-01
• First posted: 2008-10-08
• Last updated: 2010-10-13

Locations

1 site across 1 country: United States