Clinical Trials Directory

Trials / Completed

CompletedNCT00765674

Efficacy and Safety of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate-severe Hypertension

An 8 Week, Double-blind, Randomized, Parallel Group, Active-controlled Study to Evaluate the Efficacy and Safety of the Combination of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate to Severe Hypertension

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
1,191 (actual)
Sponsor
Novartis · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study evaluated the efficacy (blood pressure lowering effect) and safety of aliskiren/amlodipine/hydrochlorothiazide in patients with moderate to severe hypertension.

Conditions

Interventions

TypeNameDescription
DRUGAliskiren150 and 300 mg tablets
DRUGAmlodipine5 and 10 mg capsules
DRUGHydrochlorothiazide (HCTZ)12.5 and 25 mg capsules
DRUGPlacebotablet
DRUGPlacebocapsules

Timeline

Start date
2008-09-01
Primary completion
2009-08-01
Completion
2009-08-01
First posted
2008-10-03
Last updated
2011-05-09
Results posted
2011-05-09

Locations

12 sites across 12 countries: United States, Australia, Canada, Denmark, Germany, Israel, Italy, Latvia, Lithuania, Romania, Sweden, Turkey (Türkiye)

Source: ClinicalTrials.gov record NCT00765674. Inclusion in this directory is not an endorsement.