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Active Not RecruitingNCT00764920

Skin Imaging With Technologies in Development

Non-invasive Imaging Modalities for Assessment of Normal and Lesional Skin

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
750 (estimated)
Sponsor
University of California, Irvine · Academic / Other
Sex
All
Age
7 Years
Healthy volunteers
Accepted

Summary

The purpose of this research is to develop non-invasive imaging modalities for assessment of skin. This is a pilot study which will use multiple imaging modalities to collect information on normal and lesional skin. The researchers understand that the purpose of this study is not to evaluate any particular treatment and an investigation of a new therapeutic intervention would require an additional protocol. Skin conditions to be studied include vascular lesions, pigmentary disorders, inflammatory conditions and neoplasms.

Detailed description

Normal and lesional skin will be assessed by the following imaging modalities: 1. Laser Speckle Imaging can provide information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow. 2. Optical Coherence Tomography and Optical Doppler Tomography can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area. 3. Photon Migration Spectroscopy can provide information about the amount of blood, oxygen, fat and water is in a tissue. 4. Multi-Spectral Imaging can provide a 3 dimensional image of structures within the skin. 5. Multiphoton Microscopy can provide images of structures of the skin.

Conditions

Interventions

TypeNameDescription
DEVICEnon-invasive imaging modalities for assessment of skinskin imaging

Timeline

Start date
2008-10-01
Primary completion
2026-12-01
Completion
2026-12-01
First posted
2008-10-02
Last updated
2025-07-30

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00764920. Inclusion in this directory is not an endorsement.