Trials / Completed
CompletedNCT00763295
Is Tuberculin Skin Testing Effective in Screening for Latent Tuberculosis in Patients With HIV?
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 53 (actual)
- Sponsor
- Northwell Health · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
HIV infection highly increases the risk of progression of latent tuberculosis (TB) to active disease that therapy is recommended for all PPD-positive, HIV-infected patients, regardless of age. Sensitivity of the PPD testing is, however, dependent on a normal T cell function. Therefore, an accurate and reliable method for detection of latent tuberculosis in patients with HIV is urgently needed. This prospective study will examine the utility of interferon-gamma (IFN-γ) based assay, T-SPOT.TB,for detection of TB in HIV-infected individuals.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | T-Spot.TB test | diagnostic test |
Timeline
- Start date
- 2008-05-01
- Primary completion
- 2010-01-01
- Completion
- 2010-01-01
- First posted
- 2008-09-30
- Last updated
- 2012-10-26
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00763295. Inclusion in this directory is not an endorsement.