NCT00762164

Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol

Comparative Efficacy of a Vytorin 10/80 Tablet Split Into 4 (Estimated Dose Ezetimibe 2.5 + Simvastatin 20) Versus Simvastatin 20 Milligrams on LDL Cholesterol

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Bronx VA Medical Center · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare the efficacy of a Vytorin 10/80 tablet, an approved agent for the treatment of elevated LDL cholesterol which combines the cholesterol absorption inhibitor Ezetimibe 10 mg and simvastatin 80 mg, when split into 4 using a tablet splitter, versus a whole simvastatin 20 milligram tablet.

Conditions

• Hypercholesterolemia

Interventions

Type	Name	Description
DRUG	Vytorin	Vytorin 10/80 split into 4
DRUG	Simvastatin	Simvastatin 20 milligrams

Timeline

• Start date: 2007-03-01
• Primary completion: 2009-04-01
• Completion: 2009-05-01
• First posted: 2008-09-30
• Last updated: 2013-07-03
• Results posted: 2013-07-03

Locations

1 site across 1 country: United States