NCT00762151

A Study to Investigate the Anti-Plaque Effect of AN0128 Toothpaste

Clinical Research Study to Investigate the Anti-Plaque Effect of a Prototype Toothpaste Containing an Anacor Material Via the MGMPI Method

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Pfizer · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The objective of this study was to evaluate the anti-plaque efficacy of the Anacor prototype dentrifice as compared to commercial control products following a single use of the dentrifice.

Detailed description

The widespread successful use of triclosan as an anti-inflammatory and anti-bacterial agent is well documented. The standard dentrifice has demonstrated a robust anti-plaque and anti-inflammatory effect providing multiple benefits. There is a clear value to identify additional agents with the same dual action with a comparable or an enhanced level of efficacy. This study examined the anti-plaque efficacy following a single use of the prototype dentifrice.

Conditions

• Dental Plaque

Interventions

Type	Name	Description
OTHER	Negative Control (Regular Toothpaste)	Regular Toothpaste
OTHER	Positive Control (anti-plaque/anti-bacterial toothpaste)	Standard anti-plaque and anti-bacterial toothpaste
DRUG	Prototype (AN0128 Toothpaste)	AN0128 Toothpaste

Timeline

• Start date: 2007-11-01
• Primary completion: 2008-01-01
• Completion: 2008-01-01
• First posted: 2008-09-30
• Last updated: 2019-06-05

Locations

1 site across 1 country: United States