NCT00760760

n-3 Polyunsaturated Fatty Acids in Obesity

Impact of n-3 Polyunsaturated Fatty Acids on Adipose Tissue Inflammation in Morbidly Obese Patients

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 55 (actual)
• Sponsor: Medical University of Vienna · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Inflammation in the adipose (fat) tissue is an important condition leading to metabolic derangements and cardiovascular disease in obese patients. n-3 polyunsaturated fatty acids exert anti-inflammatory effects and prevent adipose tissue inflammation in rodent obesity. This study tests the hypothesis that n-3 polyunsaturated fatty acids ameliorate adipose tissue inflammation in morbidly obese patients.

Conditions

• Adipose Tissue Inflammation
• Morbid Obesity

Interventions

Type	Name	Description
DRUG	reesterified long-chain n-3 polyunsaturated fatty acids (EPA, DHA)	4g daily, 8 weeks
DRUG	control	equivalent amount of fat as butter

Timeline

• Start date: 2008-09-01
• Primary completion: 2014-09-01
• Completion: 2016-03-01
• First posted: 2008-09-26
• Last updated: 2016-03-16

Locations

1 site across 1 country: Austria