Trials / Completed
CompletedNCT00756938
Study of Losartan in Pediatric Patients With Hypertension (MK-0954-337)
A Phase III, Randomized, Open-Label, Parallel-Group, Dose-Ranging Clinical Trial to Study the Safety and Efficacy of MK954/Losartan Potassium in Pediatric Patients With Hypertension
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 101 (actual)
- Sponsor
- Organon and Co · Industry
- Sex
- All
- Age
- 6 Months – 6 Years
- Healthy volunteers
- Not accepted
Summary
This study will explore the dose-response of losartan as well as the safety and tolerability in children from 6 months to 6 years of age.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | losartan potassium | losartan potassium, dry powder, to be suspended in liquid and given orally, once daily; doses will start at 0.1 mg/kg, 0.3 mg/kg, and 0.7 mg/kg, respectively, in the three study arms and can be escalated up to 1.4 mg/kg (maximum dose 100 mg) until target blood pressure is reached. |
Timeline
- Start date
- 2009-03-01
- Primary completion
- 2012-08-14
- Completion
- 2012-08-14
- First posted
- 2008-09-22
- Last updated
- 2024-06-18
- Results posted
- 2014-03-03
Source: ClinicalTrials.gov record NCT00756938. Inclusion in this directory is not an endorsement.