NCT00756262

Probiotic Lactobacillus GG to Eliminate VRE Colonization

• Status: Terminated
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Tufts Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The use of LGG will be associated with elimination of VRE colonization. The primary comparison will be VRE elimination rates among those patients that receive LGG compared to those that receive placebo. The primary endpoint will be the proportion of patients with VRE at one week after cessation of administration of study medication or placebo. The investigators assume that the placebo group will have very little spontaneous elimination of VRE and that the LGG group will be more likely to have eliminated VRE colonization at the end of one week.

Conditions

• Vancomycin Resistant Enterococcal Colonization

Interventions

Type	Name	Description
BIOLOGICAL	Lactobacillus GG or Culturelle	Drug to be administered orally (capsule form). Dose=2 capsules/day for 14 days. Dosage strength= 1x10\^10 bacteria

Timeline

• Start date: 2003-03-01
• Primary completion: 2012-07-01
• Completion: 2012-07-01
• First posted: 2008-09-22
• Last updated: 2024-01-05

Locations

1 site across 1 country: United States