Trials / Completed
CompletedNCT00750308
Renin Angiotensin Aldosterone System (RAAS) and Fibrinolysis in Humans: ACEi and PE5i
Renin Angiotensin Aldosterone System (RAAS) and Fibrinolysis in Humans: ACEi
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 27 (actual)
- Sponsor
- Vanderbilt University · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
This study will measure the effect of the agent tadalafil on glucose and insulin homeostasis in people with metabolic syndrome in the presence and absence of an ACE inhibitor.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ramipril | Ramipril 10 mg per day for three weeks |
| DRUG | Tadalafil | tadalafil 10 mg every other day for three weeks |
| DRUG | placebo | placebo matching ramipril |
| DRUG | placebo | placebo matching tadalafil |
Timeline
- Start date
- 2006-12-01
- Primary completion
- 2009-01-01
- Completion
- 2009-05-01
- First posted
- 2008-09-10
- Last updated
- 2014-12-18
- Results posted
- 2010-04-12
Source: ClinicalTrials.gov record NCT00750308. Inclusion in this directory is not an endorsement.