NCT00750100

Low Dose hCG in the Late Follicular Phase

Among ICSI Patients Undergoing Antagonist Protocols With Recombinant FSH, Does Replacement of Recombinant FSH by 200 IU of hCG in the Late Follicular Phase Compared With Continuing Recombinant FSH, Result in a Similar Number of Oocytes?

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Universitair Ziekenhuis Brussel · Academic / Other
• Sex: Female
• Age: 18 Years – 36 Years
• Healthy volunteers: Not accepted

Summary

In this study,the investigators compared two protocols for controlled ovarian hyperstimulation in infertility patients requiring IVF. In the control group, the patient undergoes a standard antagonist protocol. In the study group, the administration of gonadotropins is stopped in the late follicular phase and replaced by low dose human chorionic gonadotropins. The primary endpoint of the study is the number of oocytes retrieved in both groups.

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	human chorionic gonadotropin	hCG 200IU in the late follicular phase
DRUG	recombinant gonadotropins	200 IU per day during controlled ovarian stimulation

Timeline

• Start date: 2007-09-01
• Primary completion: 2008-01-01
• Completion: 2008-11-01
• First posted: 2008-09-10
• Last updated: 2010-10-11

Locations

1 site across 1 country: Belgium