Trials / Completed
CompletedNCT00748735
Left Ventricular Lead Position in Cardiac Resynchronization Therapy
Optimal Definition of Left Ventricular Lead Position in Cardiac Resynchronization Therapy by Myocardial Deformation Imaging
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 55 (actual)
- Sponsor
- RWTH Aachen University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Left ventricular (LV) lead position has crucial impact on cardiac resynchronization therapy (CRT) success. This study will compare fluoroscopy and myocardial deformation imaging for optimal definition of LV lead position.
Detailed description
In a 16 segment model circumferential strain will be used to determine the segment with latest peak systolic circumferential strain prior to CRT, considered as the optimal LV lead target. LV lead will be defined by (1) fluoroscopy, (2) the maximal temporal difference of peak circumferential strain before-to-on CRT and (3) the earliest peak systolic circumferential strain during LV pacing. For all 3 modalities optimal LV lead position is defined as concordance or immediate neighbouring of the segment with defined LV lead position to the determined optimal target segment. At follow-up echocardiography will be performed to determine improvement in LV function and remodeling.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Implantation of a cardiac resynchronization therapy device | |
| PROCEDURE | Echocardiography (myocardial deformation imaging) |
Timeline
- First posted
- 2008-09-09
- Last updated
- 2008-09-09
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00748735. Inclusion in this directory is not an endorsement.