NCT00748618

Vitamin D Replacement After Kidney Transplant

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 116 (actual)
• Sponsor: University of Nebraska · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

Vitamin D deficiency accelerates vascular risk progression after kidney transplant.

Detailed description

This trial will assess the following aims: 1. Time to plateau vitamin D concentrations after initiating vitamin D supplements 2. Safety of vitamin D replacement based on serum and urine calcium 3. Effect of vitamin D on PTH concentration in individuals with elevated parathyroid hormone 4. Effect of vitamin D on markers of insulin resistance and inflammation

Conditions

• Kidney Transplantation
• Vitamin D Deficiency

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Standard vitamin D3 treatment	10,000 I.U./wk of vitamin D3 orally for 6 months
DIETARY_SUPPLEMENT	High dose vitamin D3 treatment	50,000 I.U./wk of vitamin D3 orally for 6 months

Timeline

• Start date: 2008-10-01
• Primary completion: 2012-04-01
• Completion: 2023-06-08
• First posted: 2008-09-08
• Last updated: 2024-10-26
• Results posted: 2024-10-26

Locations

1 site across 1 country: United States