NCT00746278

A Random Clinical Trial (RCT) of the Impact of Electrocoagulation on Ovarian Reserve

A Random Clinical Trial of the Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Excision of Ovarian Cyst

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 180 (actual)
• Sponsor: Shandong Provincial Hospital · Other Government
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Laparoscopic ovarian cystectomy is widely used for the removal of benign ovarian cysts but damage to ovarian reserve caused by electrocoagulation has recently been questioned. The purpose of this study is to investigate the impact of bipolar and ultrasonic scalpel electrocoagulation on ovarian reserve after laparoscopic excision of ovarian cyst.

Detailed description

Laparoscopic ovarian cystectomy is currently considered the treatment of choice in women with benign ovarian cyst and has gained increasing acceptance among gynecological surgeons(1). However, the safety of this technique in terms of ovarian damage to the operated gonad caused by electrocoagulation has recently been questioned. Many evidences support that the removal of ovarian cysts is associated with an injury to ovarian reserve. On the contrary, some retrospective studies did not show adverse outcomes compared with the control group (tubal infertility) . There is a lack of good clinical and scientific evidence such as randomized controlled study to report definitively the impact of electrocoagulation on ovarian reserve after laparoscopic excision of ovarian cyst.

Conditions

• Ovarian Cyst

Interventions

Type	Name	Description
PROCEDURE	Laparoscopic ovarian cystectomy using bipolar	Laparoscopic ovarian cystectomy using bipolar
PROCEDURE	Laparoscopic ovarian cystectomy using ultrasonic scalpel	Laparoscopic ovarian cystectomy using ultrasonic scalpel
PROCEDURE	Laparoscopic ovarian cystectomy using suture	Laparoscopic ovarian cystectomy using suture

Timeline

• Start date: 2008-09-01
• Primary completion: 2009-09-01
• Completion: 2010-02-01
• First posted: 2008-09-03
• Last updated: 2010-02-26

Locations

1 site across 1 country: China