Trials / Unknown
UnknownNCT00745329
The Effect of Infliximab on Sperm Quality
The Effect of Infliximab,Adalimumab, Azathioprines and 5-Aminosalicylate on Semen Quality in Men With Inflammatory Bowel Disease
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Tel-Aviv Sourasky Medical Center · Other Government
- Sex
- Male
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Background: The treatment of inflammatory bowel diseases (IBD) is based mainly on 3 compounds: 1- 5 aminosalysilates . 2- immunomodulators (Azathioprines). 3- Biologic therapies (Infliximab, Adalimumab) . There are no established data in the literature whether these therapies effects sperm quality. Given that a large number of the patients are young men in the reproductive stage of their lives , It of importance to investigate these effect. Aim: To investigate the effect of chronic treatment of any of the three therapy mentioned above, on sperm quality .
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | sperm quality test | All participants will undergo sequential sperm quality tests and blood tests |
Timeline
- Start date
- 2008-10-01
- First posted
- 2008-09-03
- Last updated
- 2008-09-03
Source: ClinicalTrials.gov record NCT00745329. Inclusion in this directory is not an endorsement.