NCT00744666

IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroids

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Hotel Dieu Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Intravitreal triamcinolone acetonide (IVTA) is a commonly employed treatment for various vitreoretinal disorders. However, approximately 23% to 50% of patients who receive IVTA develop ocular hypertension after the drug is injected into the eye. Similar to IVTA, topically administered corticosteroids eye drops result in ocular hypertension in approximately 33% of the population. It is unknown whether identifying patients who develop ocular hypertension from topical corticosteroids could be used to identify patients who are at risk for injectable IVTA. Therefore, the purpose of this study is to evaluate the efficacy of topical prednisolone 1% four times daily for one month as a screening test to reduce the incidence and severity of ocular hypertension after IVTA injection.

Conditions

• Vitreoretinal Disease
• Ocular Hypertension

Interventions

Type	Name	Description
DRUG	Prednisolone 1% topical eye drops	Prednisolone 1% 1gtt qid to the eye requiring IVTA

Timeline

• Start date: 2008-09-01
• Primary completion: 2010-06-01
• Completion: 2010-07-01
• First posted: 2008-09-01
• Last updated: 2009-08-06

Locations

4 sites across 1 country: Canada