Trials / Completed
CompletedNCT00744159
Prospective Comparison of Immunological Benefit of Laparoscopic Colectomy
Prospective Comparative Study of Immunological Benefit Between Laparoscopic Colectomy and Open Colectomy
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 84 (actual)
- Sponsor
- Samsung Medical Center · Academic / Other
- Sex
- All
- Age
- 20 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This study aimed to clarify existence of immunological benefit of laparoscopic colon cancer surgery compared to open colon surgery.
Detailed description
Patients with clinical stage Ⅲ left colon and upper rectal cancer were prospectively assigned to undergo LC (n=35) or OC (n=39). Factors related to cellular immunity of host (total lymphocyte count, CD4 lymphocyte, CD8 lymphocyte, CD4/CD8 ratio, HLA-DR expression on monocyte (mHLA-DR)) were examined preoperatively, on the 1st day of operation (POD1) and the 5th day of operation (POD5).
Conditions
Timeline
- Start date
- 2006-01-01
- Primary completion
- 2007-11-01
- Completion
- 2007-11-01
- First posted
- 2008-08-29
- Last updated
- 2008-08-29
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT00744159. Inclusion in this directory is not an endorsement.