Clinical Trials Directory

Trials / Completed

CompletedNCT00743002

A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione

A Multi-center, Double-blind, Randomized, Placebo-controlled Study of TT223 in Patients With Type 2 Diabetes Treated With Metformin and/or TZD

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
87 (actual)
Sponsor
OPKO Health, Inc. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This trial is designed to show the effect of treatment with TT223 or placebo on blood glucose control after 12 weeks of treatment with a 6 month follow-up. TT223 is administered by injection once daily to patients currently treated with Metformin and/or Thiazolidinedione.

Conditions

Interventions

TypeNameDescription
DRUGTT223 with Metformin and/or TZDDaily subcutaneous injection: 1 mg for 1 week; followed by 2 mg for 1 week; followed by 3 mg for 10 weeks
DRUGPlacebo with Metformin and/or TZDDaily subcutaneous injection: 1 mg for 1 week; followed by 2 mg for 1 week; followed by 3 mg for 10 weeks

Timeline

Start date
2008-08-01
Primary completion
2009-12-01
Completion
2009-12-01
First posted
2008-08-28
Last updated
2013-06-21

Locations

20 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00743002. Inclusion in this directory is not an endorsement.