NCT00742430

Resistance on Antithrombotic Drugs in Ischemic Heart Disease

Assessment of Aspirin and Clopidogrel Resistance in Ischemic Heart Disease Using Multiplate Function Analyser and it's Correlation With Major Adverse Cardiac Events

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 141 (actual)
• Sponsor: University of Zagreb · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether aspirin and clopidogrel resistance measured with Multiplate function analyser has a good correlation with incidence of major adverse cardiac events in patients with coronary artery disease (CAD).

Detailed description

Our plan is to enroll 180 patients with diagnosed CAD who electively undergo percutaneous coronary intervention (PCI). Blood samples will be taken just before the procedure and one day after the procedure and analysed on Multiplate function analyser. Assessing aspirin and clopidogrel resistance incidence using Multiplate platelet function analyzer we will also try to find resistance correlation with the incidence of major adverse cardiac events in a one year follow up.

Conditions

• Coronary Artery Disease

Interventions

Type	Name	Description
PROCEDURE	PCI	percutaneous coronary intervention in stable coronary artery disease

Timeline

• Start date: 2009-02-01
• Completion: 2011-08-01
• First posted: 2008-08-27
• Last updated: 2012-02-14

Locations

1 site across 1 country: Croatia