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Trials / Terminated

TerminatedNCT00739050

Effect of Simvastatin on Endothelial Function in Premenopausal Women With Systemic Lupus Erythematosus (0733-271)(TERMINATED)

Effect of Simvastatin on Endothelial Function in Premenopausal Women With Systemic Lupus Erythematosus

Status
Terminated
Phase
Phase 4
Study type
Interventional
Enrollment
4 (actual)
Sponsor
Organon and Co · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

Women with Systemic Lupus Erythematosus (SLE) are prone to cardiovascular disease. Early detection of improvement of endothelial function with simvastatin could be a clue for future intervention trials.

Conditions

Interventions

TypeNameDescription
DRUGsimvastatinsimvastatin 20mg daily at nights for 12 weeks. Tablets
DRUGComparator: Placeboplacebo daily at nights for 12 weeks. Tablets

Timeline

Start date
2007-09-19
Primary completion
2008-02-01
Completion
2008-02-01
First posted
2008-08-21
Last updated
2024-05-23
Results posted
2010-12-16

Source: ClinicalTrials.gov record NCT00739050. Inclusion in this directory is not an endorsement.

Effect of Simvastatin on Endothelial Function in Premenopausal Women With Systemic Lupus Erythematosus (0733-271)(TERMIN (NCT00739050) · Clinical Trials Directory