NCT00737490

Does Echocardiographically Guided Ventriculo-Ventricular Optimization Yield a Sustained Improvement in Echocardiographic Parameters in Cardiac Resynchronization Therapy Patients? (DEVISE CRT)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether using an echocardiogram (a painless test where ultrasound is used to see your heart) while using mild electrical stimulation from your own CRT-D device to stimulate the ventricles (the lower chambers of the heart) to squeeze one slightly earlier than the other will show a sustained increase your heart's productivity (Cardiac Output (CO)), following implantation of a Cardiac Resynchronization Device (CRT-D). We believe that squeezing some parts of the heart earlier than others may make the heart a stronger pump.

Conditions

• Cardiomyopathy
• Heart Failure

Interventions

Type	Name	Description
OTHER	"Sequential Arm" (Promote , model # 2207-36 or Atlas HF , model # V-343)	Echocardiographically guided optimized device programming: specifically sequential BiV pacing. "Sequential Arm" Using one of the FDA approved St. Jude devices, depending on MD preference.
OTHER	"Simultaneous Arm" (Promote , model # 2207-36 or Atlas HF , model # V-343)	simultaneous BiV pacing. Using one of the FDA approved St. Jude devices, depending on MD preference.

Timeline

• Start date: 2005-06-01
• Primary completion: 2009-12-01
• Completion: 2011-07-01
• First posted: 2008-08-19
• Last updated: 2014-08-01

Locations

1 site across 1 country: United States