NCT00734630

Efficacy and Safety of Nebivolol (Added to Lisinopril or Losartan) in Hypertensive Patients

A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Nebivolol Added To Antihypertensive Treatment With Lisinopril or Losartan in Patients With Hypertension.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 491 (actual)
• Sponsor: Forest Laboratories · Industry
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This study will assess blood pressure reduction with nebivolol or placebo in patients taking lisinopril or losartan.

Conditions

• Hypertension

Interventions

Type	Name	Description
DRUG	nebivolol	Encapsulated Nebivolol 5mg, 10mg, 20mg, or 40mg total daily dosage, oral administration once daily Lisinopril 10mg, 20mg total daily dosage, oral administration Losartan 50mg, 100mg total daily dosage, oral administration
DRUG	Placebo	Lisinopril 10mg, 20mg total daily dosage, oral administration Losartan 50mg, 100mg total daily dosage, oral administration

Timeline

• Start date: 2008-08-01
• Primary completion: 2010-03-01
• Completion: 2010-05-01
• First posted: 2008-08-14
• Last updated: 2011-04-26
• Results posted: 2011-04-26

Locations

75 sites across 1 country: United States