NCT00730938

The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: Presbyterian Church East Africa Kikuyu Hospital · Academic / Other
• Sex: All
• Age: 6 Months – 15 Years
• Healthy volunteers: Not accepted

Summary

The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision). We hypothesize that the fibrin is caused by a low-level infection and could be prevented by the antibiotic.

Detailed description

The study investigates whether using an antibiotic (cefuroxime) in the anterior chamber of the eye at the end of surgery for cataract in children will reduce the amount of fibrin formation.

Conditions

• Cataract
• Endophthalmitis

Interventions

Type	Name	Description
DRUG	cefuroxime	intracameral cefuroxime 0.1 ml
DRUG	Saline placebo	0.1 ml of Ringers lactate

Timeline

• Start date: 2008-02-01
• Primary completion: 2008-07-01
• Completion: 2008-08-01
• First posted: 2008-08-08
• Last updated: 2008-08-08

Locations

1 site across 1 country: Kenya