Clinical Trials Directory

Trials / Completed

CompletedNCT00730795

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine Given to PPD-Negative Adults

A Phase I Open Label, Dose-Escalation Study to Evaluate the Safety and Immunogenicity of the Recombinant Mycobacterium Tuberculosis Vaccine, Mtb72F With AS02A Adjuvant, When Administered Intramuscularly to Healthy PPD-Negative Adults

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
12 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years – 40 Years
Healthy volunteers
Accepted

Summary

This Phase I study will evaluate the safety and immunogenicity of two doses GSK Biologicals' candidate TB vaccine (692342) according to a 0, 1, 2 months schedule in PPD-negative adults.

Conditions

Interventions

TypeNameDescription
BIOLOGICALGSK's candidate Mycobacterium tuberculosis vaccine 692342Intramuscular injection, 3 doses at 0, 1, 2 months Different antigen doses (low and high)

Timeline

Start date
2004-01-01
Primary completion
2004-12-01
First posted
2008-08-08
Last updated
2008-08-08

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00730795. Inclusion in this directory is not an endorsement.