NCT00730743

Study on Clinical Outcome of Vascular Inflow Occlusion in Open Liver Resection

Open Liver Resection With or Without Vascular Inflow Occlusion: a Randomized Control Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 126 (actual)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate whether applying inflow vascular occlusion in modern liver resection is associated with better clinical outcome. Eligible patients are randomly assigned to the two surgical techniques: with or without the application of inflow vascular occlusion. Patients outcome including liver function recovery, operative time and blood loss are compared.

Conditions

• Hepatectomy

Interventions

Type	Name	Description
PROCEDURE	Intermittent Pringle maneuver	Pringle maneuver is performed by isolation of the hepatoduodenal ligament which is then encircled and occluded with atraumatic vascular clamp. The clamp is applied for 15 minutes followed by unclamping for 5 minutes and repeated till end of liver transection. Limits of clamp cycle: 3 cycles for cirrhotic liver; 4 cycles for non-cirrhotic liver.

Timeline

• Start date: 2008-05-01
• Primary completion: 2011-05-01
• Completion: 2011-08-01
• First posted: 2008-08-08
• Last updated: 2015-02-04

Locations

1 site across 1 country: China