Clinical Trials Directory

Trials / Completed

CompletedNCT00730223

Genetic Determinants of the Metabolism of Non-nucleoside Reverse Transcriptase Inhibitors

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
33 (actual)
Sponsor
Vanderbilt University · Academic / Other
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

To see if certain variations in the CYP2B6 gene contribute to differences in plasma drug levels and central nervous system side affects in people who take nevirapine or efavirenz.

Conditions

Interventions

TypeNameDescription
DRUGNevirapine and Efavirenzsingle oral dose 200mg of nevirapine and single oral dose 600 mg of efavirenz

Timeline

Start date
2004-03-01
Primary completion
2006-03-01
Completion
2009-08-01
First posted
2008-08-08
Last updated
2013-02-15

Source: ClinicalTrials.gov record NCT00730223. Inclusion in this directory is not an endorsement.