NCT00729911

Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD

Ablation vs. Amiodarone for Treatment of Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted ICD/CRTD

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 203 (actual)
• Sponsor: Texas Cardiac Arrhythmia Research Foundation · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

1. To determine if catheter-based atrial fibrillation (AF) ablation is superior to Amiodarone treatment for symptomatic persistent/permanent AF in ICD/CRTD patients with an impaired left ventricular function. 2. Hypothesis: AF ablation is better than Amiodarone for subjects with symptomatic persistent or permanent AF and impaired LV function in terms of recurrence of AF, quality of life, 6-minute walk distance, EF and total number of hospitalizations.

Conditions

• Heart Failure

Interventions

Type	Name	Description
PROCEDURE	Atrial Fibrillation ablation	Radio-frequency catheter ablation of atrial fibrillation
DRUG	Amiodarone	Taken orally on a daily basis.

Timeline

• Start date: 2008-10-01
• Primary completion: 2014-12-01
• Completion: 2015-12-01
• First posted: 2008-08-08
• Last updated: 2019-04-10

Locations

1 site across 1 country: United States