Trials / Unknown
UnknownNCT00728546
NAT2 in Re-challenge of INH in Patients With Hepatitis
The Application of the N-acetyltransferase 2 (NAT2) Genotyping in Re-challenge Protocol of Isoniazid (INH) Titration in Patients With Anti-TB Medications-induced Hepatitis
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- Sponsor
- National Taiwan University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Apply the information of NAT2 genotyping into the re-challenge protocol of INH titration in patients with anti-TB medication induced hepatitis.
Detailed description
adjusting INH dose according to NAT2 genotyping and serum concentration of INH.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Isoniazid (Rifinah) | The dose of the re-challenged INH is followed by the results of the genotyping of NAT2 in each patient. |
Timeline
- Start date
- 2008-06-01
- Primary completion
- 2015-11-01
- Completion
- 2015-11-01
- First posted
- 2008-08-06
- Last updated
- 2012-12-27
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT00728546. Inclusion in this directory is not an endorsement.