Clinical Trials Directory

Trials / Completed

CompletedNCT00727753

VEGF-antagonism and Endothelial Function in Age-related Macular Degeneration (AMD)

Effects of Vascular Endothelial Growth Factor Antagonism With Ranibizumab or Bevacizumab in Patients With Neovascular Macular Degeneration

Status
Completed
Phase
Study type
Observational
Enrollment
54 (actual)
Sponsor
University of Zurich · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The objective of this study is to evaluate the effects of 2 intravitreal injections with Ranibizumab or Avastin on endothelial function in subjects with neovascular macular degeneration compared to patients with dry AMD.

Conditions

Interventions

TypeNameDescription
DRUGRanibizumabranibizumab (0.5 mg) will be injected intraocular
DRUGBevacizumabBevacizumab (1.25 mg) will be injected intraocular
OTHERNo treatmentNo treatment

Timeline

Start date
2008-07-01
Primary completion
2012-12-01
Completion
2013-10-01
First posted
2008-08-04
Last updated
2015-05-28

Locations

1 site across 1 country: Switzerland

Source: ClinicalTrials.gov record NCT00727753. Inclusion in this directory is not an endorsement.

VEGF-antagonism and Endothelial Function in Age-related Macular Degeneration (AMD) (NCT00727753) · Clinical Trials Directory