Clinical Trials Directory

Trials / Completed

CompletedNCT00724971

Study Evaluating The Safety And Tolerability Of Combination Therapy Inotuzumab Ozogamicin (CMC-544) And Rituximab

A Phase 1 Study Of Cmc-544 Administered In Combination With Rituximab In Subjects With B-cell Non-hodgkin's Lymphoma

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
10 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
20 Years – 75 Years
Healthy volunteers
Not accepted

Summary

To assess the tolerability and the initial safety profile of Inotuzumab Ozogamicin (CMC-544) in combination with Rituximab in patients with B-Cell Non-Hodgkin's lymphoma (NHL).

Conditions

Interventions

TypeNameDescription
DRUGInotuzumab Ozogamicin (CMC-544)1.8 mg/m2, IV on day 2 of each 28 day cycle; up to 8 cycles unless PD, unacceptable toxicity, or subject's refusal occurs.
DRUGRituximab (Rituxan)375 mg/m2, IV on day 1 of each 28 day cycle; up to 8 cycles unless PD, unacceptable toxicity, or subject's refusal occurs.

Timeline

Start date
2008-07-04
Primary completion
2010-03-10
Completion
2010-03-10
First posted
2008-07-30
Last updated
2019-03-15
Results posted
2019-03-15

Locations

4 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT00724971. Inclusion in this directory is not an endorsement.