Clinical Trials Directory

Trials / Completed

CompletedNCT00723892

Adherence in Patients Receiving PegIntron/Rebetol for Hepatitis C in Conjunction With a Psychotherapy Support Program (Study P04252)

Observatory on Treatment Adhesion in Patients Suffering From Hepatitis C Chronic Treated With ViraferonPeg® Injected / Rebetol® in Conjunction With a Psychotherapeutic Assistance Program

Status
Completed
Phase
Study type
Observational
Enrollment
614 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Several psychiatric adverse events (eg, depression, fatigue, psychoses, behavior troubles, anxiety, irritability, deteriorated concentration, and insomnia) that are likely to occur during the treatment course with PegIntron plus Rebetol may prompt patients to discontinue their treatment early. The goal of this study is to assess whether a psychotherapy support program may contribute to a better adherence rate.

Detailed description

Enrollment of participants will occur in a sequential order of treatment initiation.

Conditions

Interventions

TypeNameDescription
BIOLOGICALPeginterferon alfa-2b (PegIntron)Peginterferon alfa-2b (PegIntron) was administered based on the prescribed dose. The average dose for PegIntron was a weekly injection of 1.5 ± 0.3 μg\^kg\^week
DRUGRebetol (Ribavirin)Rebetol was administered orally based on the prescribed dose. The average dose for Rebetol was 950 ± 167.2 mg\^day
BEHAVIORALPsychotherapy support programEach site has implemented a psychotherapy support program.

Timeline

Start date
2005-07-01
Primary completion
2009-05-01
Completion
2009-05-01
First posted
2008-07-29
Last updated
2015-10-30
Results posted
2010-09-20

Source: ClinicalTrials.gov record NCT00723892. Inclusion in this directory is not an endorsement.