NCT00723268

Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Mashhad University of Medical Sciences · Academic / Other
• Sex: All
• Age: 15 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether low doses of prednisolone, or colchicine are effective in the treatment of oral aphthae.

Detailed description

Treatment of recurrent aphthous stomatitis (RAS) remains, to date, empirical and non-specific. The main goals of therapy are to minimize pain and functional disabilities as well as decrease inflammatory reactions and frequency of recurrences.

Conditions

• Oral Aphthae

Interventions

Type	Name	Description
DRUG	Prednisolone	5MG Prednisolone per day for 3 months
DRUG	Colchicine	0.5 MG Colchicine per day for 3 months

Timeline

• Start date: 2007-05-01
• Primary completion: 2008-08-01
• First posted: 2008-07-28
• Last updated: 2008-07-29

Locations

1 site across 1 country: Iran