NCT00722527

Molecular Biology of Polycythemia and Thrombocytosis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: University of Utah · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Our study is designed to characterize the clinical picture and genetic pattern of Polycythemia and Thrombocytosis. The purpose of this project is to find a gene and its mutation that causes these disorders. When this is accomplished, new therapies to control and eventually cure the disorder can be designed.

Detailed description

Our hypothesis is that genes and their mutation are causative of certain types of polycythemia and thrombocytosis. These will be sought for by genetic and cell biology means. The purpose of the study is to identify the molecular defect of these disorders. 5-7 teaspoons of peripheral blood will be drawn on all study subjects. After DNA is obtained, linkage analysis and/or mutation analysis will be performed.

Conditions

• Polycythemia
• Thrombocytosis

Timeline

• Start date: 2006-07-01
• Primary completion: 2028-07-01
• Completion: 2028-07-01
• First posted: 2008-07-25
• Last updated: 2026-03-09

Locations

1 site across 1 country: United States