NCT00721097

Predictive Factors for Exacerbation Outcome in Severe Refractory Asthmatics

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Asthma is a chronic inflammatory disease, affecting up to 10 % of the general population in developed countries. Corticosteroids are necessary to control symptoms, but induce adverse events sometimes intolerable. In severe asthma, which represent 5 to 10% of global asthma, corticosteroids frequently fail to prevent severe exacerbations, leading to emergency care, hospitalization and sometimes death. The aim of this study is to identify predictive factors specific for exacerbation outcome which will lead to a minor increase in treatment in order to prevent exacerbations, while minimizing drug adverse effects.

Conditions

• Asthma
• Chronic Inflammatory Diseases

Interventions

Type	Name	Description
OTHER	spirometry, and blood taken	each month during one year

Timeline

• Start date: 2008-06-01
• Primary completion: 2011-05-01
• Completion: 2011-05-01
• First posted: 2008-07-23
• Last updated: 2013-09-30

Locations

1 site across 1 country: France