Trials / Completed
CompletedNCT00716924
CASTLE (Clopidogrel And Serum Troponin Level Elevation)
Clopidogrel 600 mg and 300 mg as a Loading Dose Prior to Percutaneous Coronary Intervention And Serum Troponin Level Elevation: A Pilot Study
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 155 (actual)
- Sponsor
- Sanofi · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Primary Objective: To test if 600 mg of clopidogrel loading dose administered ≥ 6 and ≤ 24 hours prior to PCI produce a greater decrease of periprocedural release of biochemical markers (CK, CK-MB, and troponin-T and/or I) of myocardial necrosis, compared to 300 mg loading dose, given ≥ 6 and ≤ 24 hours prior to PCI or 600 mg loading dose of clopidogrel, administered immediately (≤ 45 minutes) before PCI.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Clopidogrel | 300 mg |
| DRUG | Clopidogrel | 600 mg |
Timeline
- Start date
- 2004-05-01
- Primary completion
- 2006-02-01
- First posted
- 2008-07-16
- Last updated
- 2009-09-25
Locations
1 site across 1 country: Mexico
Source: ClinicalTrials.gov record NCT00716924. Inclusion in this directory is not an endorsement.