Trials / Completed
CompletedNCT00716846
Effects of Statins on the Pharmacokinetics for Midazolam in Healthy Volunteers
Effects of Three Statins, Simvastatin, Atorvastatin, and Pitavastatin, on the Pharmacokinetics for Midazolam in Healthy Volunteers
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 11 (actual)
- Sponsor
- Hamamatsu University · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to investigate whether statins have any influence on cytochrome P450 (CYP) 3A4 enzyme activity using a probe drug midazolam.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | simvastatin | 10mg, 2 weeks |
| DRUG | atorvastatin | 10mg |
| DRUG | pitavastatin | 2mg |
Timeline
- Start date
- 2006-06-01
- Primary completion
- 2008-07-01
- Completion
- 2008-08-01
- First posted
- 2008-07-16
- Last updated
- 2011-09-07
Locations
1 site across 1 country: Japan
Source: ClinicalTrials.gov record NCT00716846. Inclusion in this directory is not an endorsement.