NCT00714142

Renal Blood Flow Measurement With Positron Emission Tomography (PET)

Renal Blood Flow Measurement With PET

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Jeffrey L. Lacy · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Two investigational chemical tracers, 62Cu-ethylglyoxal bis(thiosemicarbazone) (62Cu-ETS) and 15O-water, will be used in this study to look at how blood moves through the kidneys. The purpose of the study is to see if 62Cu-ETS is effective in showing the blood supply to the kidneys compared to 15O-water. The tracer mixes with the blood and moves through the body. Using positron emission tomography (PET scan) the researchers can see the tracer and can learn more about how the blood moves through the kidneys. The study invites participants who are healthy, without any heart or kidney disease, patients who have kidney disease that require dialysis, and patients who may have a blockage in one of the arteries supplying blood to the kidneys.

Conditions

• Renal Failure
• Renal Artery Stenosis

Interventions

Type	Name	Description
DRUG	62Cu-ethylglyoxal bis(thiosemicarbazone)	15-25 mCi, IV
DRUG	15O-water	10-20 mCi, IV
PROCEDURE	Positron Emission Tomography	PET Scan

Timeline

• Start date: 2008-08-01
• Primary completion: 2009-04-01
• Completion: 2009-04-01
• First posted: 2008-07-14
• Last updated: 2017-04-19

Locations

1 site across 1 country: United States