NCT00711477

A Study Using Functional Magnetic Resonance Imaging (fMRI) to Assess the Effects of Naltrexone SR/ Bupropion SR Therapy in Overweight or Obese Subjects

Naltrexone Sustained Release (SR) 32 mg and Bupropion Sustained Release (SR) 360 mg Combination Therapy in Functional Magnetic Resonance Imaging (fMRI) Changes in Overweight or Obese Subjects

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Orexigen Therapeutics, Inc · Industry
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to assess the effect of naltrexone SR/bupropion SR (NB) on brain function in response to food cues using functional magnetic resonance imaging in overweight or obese subjects.

Conditions

• Obesity

Interventions

Type	Name	Description
DRUG	Naltrexone SR 32 mg/bupropion SR 360 mg/day
DRUG	Placebo
OTHER	fMRI scan	fMRI to assess the effects of the drug/placebo on areas of the brain

Timeline

• Start date: 2008-09-01
• Primary completion: 2010-06-01
• Completion: 2010-06-01
• First posted: 2008-07-09
• Last updated: 2015-01-06
• Results posted: 2015-01-06

Locations

1 site across 1 country: United States