NCT00707525

Embryo Aneuploidies and Ovarian Stimulation

Incidence of EmbyoO Aneuploidies in Natural Versus Stimulated Cycles in the Same Women.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: —
• Sponsor: Instituto Valenciano de Infertilidad, IVI VALENCIA · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

There is a considerable concern about the effects of controlled ovarian hyperstimulation (COH) for In Vitro Fertilization- Embryo Transfer (IVF-ET) on embryo quality and on the incidence of chromosomal abnormalities in oocytes and embryos. The main question remaining is if COH may increase the aneuploidies rate in young and healthy women. Therefore, the primary endpoint of the present study is to analyse the incidence of chromosomal abnormalities in this group of patients (oocyte donors), either in oocytes obtained after a natural cycle or in those retrieved after a COH cycle. To get rid of the male factor influence, donated sperm will be used.

Conditions

• Embryo Aneuploidies

Interventions

Type	Name	Description
PROCEDURE	Preimplantation Genetic Diagnosis	Preimplantation Genetic Diagnosis (PGD) is performed on the embryos resulting from these natural and stimulated cycles.

Timeline

• Start date: 2008-02-01
• Primary completion: 2010-02-01
• Completion: 2010-02-01
• First posted: 2008-07-01
• Last updated: 2010-03-26

Locations

1 site across 1 country: Spain