NCT00705497

Radiofrequency Ablation of Tumors

Radiofrequency Ablation of Tumors (RFA) A Phase I Study

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: St. Jude Children's Research Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Background: This prospective study was designed to be the first to evaluate the toxicity of radiofrequency ablation (RFA) in patients with recurrent pediatric solid tumors. Methods: From 2003 through 2006, we conducted a phase I, IRB-approved study of RFA for recurrent solid tumors. A multidisciplinary cancer management team selected appropriate candidates for the study. Imaging-guided RFA was performed percutaneously. Response was assessed at 3 months. Repeat RFA was performed for some incompletely ablated or new lesions.

Conditions

• Primary Tumors
• Metastatic Tumors

Interventions

Type	Name	Description
PROCEDURE	Radiofrequency Tumor Ablation	Radiofrequency tumor ablation (RFA) is an imaging guided percutaneous or intra-operative procedure that uses a probe on the end of a sharp needle that is inserted directly into the tumor. The tumor is ablated by heating the probe (using electrical current alternating at radio frequency) which raises the temperature of the tumor potentially causing irreversible cell death.

Timeline

• Start date: 2003-01-01
• Primary completion: 2008-10-01
• Completion: 2008-10-01
• First posted: 2008-06-26
• Last updated: 2017-04-26

Locations

1 site across 1 country: United States